Deciphering Epigenetic Regulation with Single Cell ATAC-Seq
Chromium Single Cell ATAC is a powerful epigenomic tool to unravel cell type-specific regulatory networks. It has previously been demonstrated that this solution enables the profiling of accessible chromatin regions from tens of thousands of single cells at a time, thus enumerating active DNA regulatory elements, such as cis-acting DNA elements (e.g., enhancers and promoters) and trans-acting factors (e.g., transcription factors). These accessible chromatin regions can be used to distinguish cell types within complex populations and infer transcriptional regulatory mechanisms, making single cell ATAC-seq data especially useful for studying gene regulation at single cell resolution.
Chromium Single Cell ATAC is a powerful epigenomic tool to unravel cell type-specific regulatory networks. It has previously been demonstrated that this solution enables the profiling of accessible chromatin regions from tens of thousands of single cells at a time, thus enumerating active DNA regulatory elements, such as cis-acting DNA elements (e.g., enhancers and promoters) and trans-acting factors (e.g., transcription factors). These accessible chromatin regions can be used to distinguish cell types within complex populations and infer transcriptional regulatory mechanisms, making single cell ATAC-seq data especially useful for studying gene regulation at single cell resolution.