Chromium Instrument Family

A single cell instrument for every stage

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Chromium instrument family including Chromium X, Chromium Connect, and Chromium Controller

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Welcome to the Chromium instrument family

Whether you’re just starting out with single cell, expanding your capabilities, or seeking an automated way to partition individual cells and generate barcoded, sequencing-ready libraries, you're covered. Our proven Next GEM technology provides a trusted path to advance your understanding of cell diversity and function.

  • Partition 100s to 100,000s of single cells in minutes.

  • Run kitted, validated assays for gene expression, immune profiling, and multiomic analysis.

  • Find expert support for each step of your single cell experiment.

  • Rely on proven Next GEM technology featured in 3,500+ publications.

  • Choose from a flexible range of cell throughputs and manual and automated workflows.

  • Streamline your workflow with easy-to-use platforms and intuitive interfaces.

Choose the instrument that's right for you

Instruments

Chromium X Series

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Chromium Connect

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Chromium Controller

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Description

Expand your single cell capabilities with the most advanced hardware and highest throughput flexibility, enabling multiomic analysis of hundreds to millions of cells.

Combine single cell partitioning, barcoding, and/or library construction with standardized, automated workflows to maximize your productivity.

Perform multiomic analysis of hundreds to tens of thousands of single cells with this compact system.

Assay Compatibility

Chromium X and iX
  • Single Cell Gene Expression LT
  • Single Cell Gene Expression
  • Single Cell Immune Profiling
  • Single Cell ATAC
  • Single Cell Multiome ATAC + Gene Expression
  • Single Cell Gene Expression Flex
Chromium X only
  • Single Cell Gene Expression HT
  • Single Cell Immune Profiling HT
  • Single Cell Gene Expression
  • Single Cell Immune Profiling
  • Single Cell Gene Expression LT
  • Single Cell Gene Expression
  • Single Cell Immune Profiling
  • Single Cell ATAC
  • Single Cell Multiome ATAC + Gene Expression

Cell Throughput

Throughput determined by assay type
Chromium X

Low, Standard, and High

100-730,000 singlets per run*

Single Cell Gene Expression Flex - 500-1,024,000 singlets per run*

Chromium iX

Low and Standard

100-140,000 singlets per run

High (Single Cell Gene Expression Flex only)

500-1,024,000 singlets per run*

Standard

500–80,000 singlets per run

Low and Standard

100–140,000 singlets per run

Workflow Type

Manual

Automated

Manual

Workflow Steps

  • Single cell partitioning (GEM generation)
  • Single cell partitioning (GEM generation)
  • Library construction
  • Single cell partitioning (GEM generation)

Connectivity

Optional

Compatible with 10x Cloud instrument management

Optional

Connects to the internet

No

*Singlets are single cells or nuclei after multiplet removal