Choice
Start from FFPE blocks or pre-sectioned tissue on glass slides.
Confidence
Pre-screen to find the most biologically relevant tissue sections.
Flexibility
Integrate seamlessly with standard histology workflows for H&E and IF staining.
Simplified sample processing
- The Visium CytAssist is a compact instrument designed to simplify the Visium workflow by facilitating the transfer of transcriptomic probes from standard glass slides to Visium slides, enabling spatial profiling insights to be gained from an expanded range of FFPE samples.
Simplified sample management
It all starts with a standard glass slide. The Visium CytAssist enables users to start with tissue on standard glass slides, allowing input tissue to be prepared, stained, and imaged using standard histology workflows.
Expanded sample access
Compatible with H&E or immunofluorescently stained FFPE tissue sections, the CytAssist instrument allows you to use pre-sectioned and pre-stained tissues with 6.5 x 6.5 mm or 11 x 11 mm Visium Capture Area slides.
Maximized spatial insights
Pre-screen tissue sections and then use the instrument for precise manual alignment of tissue section to Visium Capture Areas making the most of your spatial discovery studies.
Visium workflow with CytAssist
Facilitate transfer of transcriptomic analytes in FFPE samples with Visium CytAssist. In the Visium CytAssist workflow, sectioning, deparaffinization, and staining and imaging (H&E or IF) take place on a standard glass slide. After probe hybridization, two standard glass slides and a two–Capture Area Visium slide are placed in the CytAssist instrument so that the tissue sections on the standard slides can be aligned on top of the two Visium Capture Areas. Within the instrument, a brightfield image is captured to provide spatial orientation for data analysis, followed by hybridization of transcriptomic probes to the Visium slide. The remaining steps, starting with probe extension, follow the standard Visium for FFPE workflow outside of the instrument.
Visium CytAssist
A compact instrument to facilitate the transfer of analytes from sectioned tissues to Visium Slides.
Visium gene expression reagents
Compatible with Visium Spatial Gene Expression for FFPE.
Data visualization software
Our analysis pipelines
Our visualization software
World-class technical and customer support
Contact our support team by phone or email.
Frequently Asked Questions
Visium CytAssist enables access to FFPE samples archived in blocks or pre-sectioned onto standard glass slides. Existing samples can be stained with H&E staining or IF antibodies on the glass slides before introduction to the Visium workflow.
The CytAssist will be compatible with human and mouse FFPE samples.