Chromium instruments are powered by Next GEM technology
Next GEM technology is built on a novel chip architecture that enables high-throughput single cell analysis with our Chromium instruments. This innovative system includes chips and compatible reagents, and is offered for the full breadth of our single cell product portfolio:
- Chromium Single Cell Gene Expression
- Chromium Single Cell Immune Profiling
- Chromium Single Cell ATAC
- Chromium Single Cell Multiome ATAC + Gene Expression
- Chromium instruments
Reagent delivery system
All fragments produced within a partition share a common barcode
Next GEM technology creates a unique reagent delivery system that partitions cells or nuclei and prepares sequencing libraries in parallel, such that all fragments produced within a partition share a common barcode. This process ensures that a sample maintains its single cell characteristics, with each barcode enabling a fragment to be traced back to its cell or nucleus of origin. In this way, barcoded fragments can be processed in bulk downstream and still be linked to individual cells.
A simple workflow combines large partition numbers with a massively diverse barcode library to generate >100,000 barcode-containing partitions in a matter of minutes.
Lab integration
Seamless integration into existing lab workflows
Chromium single cell workflows fit easily into your existing lab infrastructure. The end-to-end single cell sequencing solutions include sample preparation support and turnkey data analysis and visualization tools.